Buffer System

Buffer systems * bar major changes in pH of body fluids by removing or relinquish H+ * act quickly to prevent excessive changes in H+ concentration. Bodys major extracellular buffer system is bicarbonate-carbonic superman buffer system. There are 20 parts of (HCO3) to superstar part of (H2CO3). - 201. When the ratio is no longer maintained, it will result to acid-base im labyrinthine sense. carbon dioxide is a potential acid when dissolved in water, it becomes carbonic acid. Lungs infra the control of medulla control the carbonic acid gas, and thus the carbonic content of ECF.They do so by adjusting ventilation in response to the amount of CO2 in the blood. A rise in PaCO2 is powerful response to stimulant. respiratory Compensation * is a mechanism by which plasma pH keep be adapted by varying therespiratory rate. * breathingis altered to modify the amount of CO2in circulation. Kidneys regulate bicarbonate take in the ECF they can regenerate bicarbonate ions as swell up as r eabsorb them from renal tubules. Renal compensation for imbalances is relatively belatedly (a matter of hours or days). The kidneys have two important roles in the maintaining of the acid-base balance 1. to reabsorb bicarbonate 2. to excrete hydrogen ions into urine. Bicarbonate Buffer strategy * 2 components (H2CO3) carbonic acid, a watery acid and (NaHCO3) a weak base. * 1. If a potential pH change is created by a loyal acid, the ff. takes place HCL + NaHCO3 NaCl + H2CO3 (strong acid) (weak acid) 2. If a potential pH changes is created by strong base, the ff. answer takes place NaOH + H2CO3 H2O + NaHCO3 (strong base) (weak base)